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Citrix Workspace has both an offline and online installer. The offline one comes with the prerequisites built in, so dependencies don't have to be set up. The offline installer requires a login on the vendor's website to be downloaded, however.
We would like to be able to keep Primavera P6 up to date. If updates between major versions (v8 to v18) are not possible it would still be a benefit to update within the version (v19.1 to 19.2)
MODELLER is used for homology or comparative modeling of protein three-dimensional structures. Useful for University biopharmaceutical research and teaching. I believe it uses NULLSOFT installer switches.